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doi: 10.1073/pnas.0906773106

Safety in specific populations Older adults: Generally safe, may need dose adjustment for reduced kidney function

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any new or worsening psychiatric symptoms deserve immediate contact with a provider

This additional receptor engagement produces a mechanistically distinct research profile, particularly relevant to hepatic biology and thermogenesis research

doi: 10.1146/annurev-nutr-071714-034250 197 SebaiHHovspianSRistorcelliEAouaniELombardoDFayetG