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In patients with coronary artery disease, both high-intensity and moderate-intensity exercise training for 4 weeks significantly increased the coronary collateral flow index, enhanced exercise capacity, and raised the ischemic threshold, with comparable effects between the two training intensities

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This knowledge not only helps in drug development but also allows clinicians to approach treatment with a more nuanced understanding of their patients unique physiological responses

The significance of these models extends beyond aesthetic concerns, indicating that lipodystrophy may precipitate profound metabolic disturbances