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Not a huge difference on paper, but clinically significant for both efficacy and side effects

However, patients should report persistent vomiting or diarrhea that could lead to dehydration and acute kidney injury, particularly in those with underlying renal impairment

Patients with other thyroid conditions like papillary thyroid cancer, hypothyroidism, or thyroid nodules are not contraindicated based on thyroid history alone

Food and Drug Administration (FDA) for chronic weight management in patients with obesity or overweight, and it has proven to be an effective weight loss aid: clinical trial participants who took Wegovy injections lost around 21% of their body weight at the highest dose (7.2mg per week), while those who took Wegovy pills lost an average of 14% of their body weight at the highest dose (25 mg per day)

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Ozempic is included, although the document notes that it requires prior authorization