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Important for the regulation of energy and glucose homeostasis, a high number of VANs contain receptors for gut peptides released by EECs, and the physiological function of these VANs has been recently elucidated via new advances in the ability to characterize and target specific neural populations

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Despite demonstrating robust glycemic efficacy, both agents were eventually discontinued due to distinct tolerability and safety concerns, diverging in severity and clinical implications

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Epidermal Growth Factor (EGF): Encourages new skin cell growth to reduce fine lines and wrinkles