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B12 shots are beneficial for individuals whose bodies have difficulty absorbing the vitamin through oral supplements due to a lack of intrinsic factor

Adverse reaction / Side effects: Rare allergic reactions (rash, itching, anaphylaxis)

Gastrointestinal symptoms, while frequent, typically improve within 48 weeks as the body adjusts to therapy

Absorption It is primarily found in animal protein, which must be broken down in the stomach for adequate absorption

Loads must be spread among several vessels, also increasing costs and creating an unwelcome extra expense for German industry currently showing signs of recovery

Route/evidence mismatch: the pivotal mouse study tested subcutaneous injection at a fixed research dose (20 mg/kg, three times daily) the oral capsule use that is actually sold and discussed commercially has not itself been directly tested in that published research