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10.1073/pnas.75.3.1213 46 LitwackG.KettererB.AriasI

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(2014) reported that induction of oxidative stress in C2C12-differentiated myotubes promoted significant mitochondrial dysfunction in a time-dependent manner, accompanied by decreased expression of MyHC and myogenic regulatory factors (MyoD, myogenin, MRF4) and induction of apoptosis [314]

Though the results can be observed very quickly, the most dramatic results will be visible four to six weeks following the treatment

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