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2 Digestive Issues This may include chronic vomiting and persistent diarrhoea that cannot be attributed to an infection or known illness

Some studies use an insufficiency threshold, in addition to a deficiency threshold

Dose: 100-250mcg Frequency: Daily or every other day Timing: 30-60 minutes before bed Duration: 4-8 weeks, followed by 2-4 week break At these doses, most users report noticeable improvements in sleep onset, depth, and morning alertness

Overarching Principle The fundamental principle of regulation of medicines is to optimise timely access to effective treatments while reducing the risk of harm from improper use

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