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Jensterle M, Salamun V, Kocjan T, Vrtacnik Bokal E, Janez A (2015) Short term monotherapy with GLP-1 receptor agonist liraglutide or PDE 4 inhibitor roflumilast is superior to metformin in weight loss in obese PCOS women: a pilot randomized study

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Potential Side Effects (If Misused) While well-tolerated when dosed properly, side effects can occur if: Dose is too high Used for too long without a break Taken in a fasted or low-blood-sugar state Possible effects include: Mild hypoglycemia (shakiness, dizziness, hunger) Local injection site irritation Temporary water retention Headache or lethargy IGF-1 therapy is generally well tolerated, but dosage, duration, and patient context significantly affect side effect profiles. Cao, J

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Novo Nordisks announcement comes shortly after the drugmaker, along with rival Eli Lilly, announced a major deal with the Trump administration that will broaden their access to the Medicare and Medicaid markets in exchange for reducing their prices