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Additional authors include Sofiya Matsekyo and Heribert Schunkert

Although this conclusion is not supported by exhaustive experiments, these findings still provide the possibility that Sema modulates ventricular muscle through acetylcholine

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Immediate medical attention (via NHS 111 or emergency services) is required if patients develop: Severe, persistent abdominal pain (possible pancreatitis) Marked reduction in urine output or complete cessation Confusion or altered consciousness Severe allergic reactions (rash, difficulty breathing, facial swelling) Healthcare professionals should establish clear safety-netting arrangements , ensuring patients understand when and how to seek help

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